Transformation of simple raw materials in a Ferment-Peptide Complex by a process that combines Natural ferment with a natural origin peptide
INNOVACTIVE BARRIERFERM
a protective barrier ferment which prevents dehydration supporting a healthy skin microbiota

TECHNOLOGY
BIO FERMENTATION
EFFICACY STUDIES
Protective activity (TEWL)
Moisturizing activity
Promoting adhesion of
beneficial skin bacteria
DOSAGE
1-3%
REGULATORY
EU AU CN KR US CA JP
Flowchart for Innovactive Barrierferm preparation
INNOVACTIVE FERMENTATION STRATEGY
Bacillus Subtilis originally obtained from Natto (the oldest Japanese food) during soybeans lactic fermentation, is fermented in the laboratory under controlled technological conditions in a specific medium with natural substrates and natural origin peptides having cosmetic properties.
During fermentation process, Bacillus Subtilis sp. Natto produces several bio actives peptides and enzymes playing key roles in skin cells.
The INNOVACTIVE FERMENTATION STRATEGY to obtain a Ferment-Peptide Complex is based on the addition of peptide during natural fermentation of Bacillus Subtilis grown with plant-derived nutrients.
INNOVACTIVE BARRIERFERM
Ferment-Peptide Complex derived from natural fermentation in which Bacillus Subtilis grows in a specific medium including Acetyl heptapeptide-4 to synergize with peptides produced by
the bacteria.
KEY ACTIVE INGREDIENTS AND THEIR FUNCTIONS
At the end of fermentation, the bacteria are filtered and lysed to obtain a concentrate rich in active ingredient such as:
- Vitamins Group B/K2/C
- Biologically active peptides
- Antioxidants
- Peptides and Proteins
- Catalase enzyme
- Lipase enzyme
Peptides and enzymes are titrated as total proteins and specific enzymatic activities which together with the B Group Vitamins make the Ferment-Peptide Complex particularly effective in several activities.
In the BARRIERFERM particularly:
Bacillus Subtilis Ferment is a key for microbiota balance, barrier reinforcement, moisturizing and protective activity.
Acetyl heptapeptide-4 boosts the skin’s own defense system by promoting microbiota balance, diversity and growth of beneficial bacteria by improving skin.
INNOVACTIVE BARRIERFERM EFFICACY
- Reinforces skin barrier and its functionality
- Supports and protects the healthy microbiome
- Promotes the adhesion of beneficial bacteria to the skin
- Improves protection to prevent dehydration
- Moisturizing activity
- Antioxidant protection from pollution, blue light and UV
IN VIVO EFFICACY TEST CARRIED OUT USING A CREAM
CONTAINING 3% OF BARRIERFERM
Evaluation of the moisturizing efficacy
after 15 minutes and 2 h

Evaluation of the protective activity
after 15 y 30 minutes

IN VIVO EFFICACY TEST CARRIED OUT USING A CREAM
CONTAINING 1% OF BARRIERFERM
Evaluation of the moisturizing efficacy
after 15 minutes and 2 h

Evaluation of the protective activity
after 15 y 30 minutes

TECHNICAL PRODUCT DATA
- INCI: Glycerin, Bacillus Ferment Filtrate, Acetyl heptapeptide-4.
- Solubility: water soluble.
- pH: 6-8.
- Colour: colorless-yellowish
- Preservative Free
- Recommended dose: 1-3%
Brochure
Interested in accelerating your research with us?
Your success is our priority. If you have a question about sales, customer support, media, or investor relations, our team is ready to answer all your questions.