A company inspired by nature and supported by science

Transformation of simple raw materials in a Ferment-Peptide Complex by a process that combines Natural ferment with a natural origin peptide

INNOVACTIVE BARRIERFERM

a protective barrier ferment which prevents dehydration supporting a healthy skin microbiota

TECHNOLOGY

BIO FERMENTATION

EFFICACY STUDIES

Protective activity (TEWL)
Moisturizing activity
Promoting adhesion of beneficial skin bacteria

DOSAGE

1-3%

REGULATORY

EU AU CN KR US CA JP

Flowchart for Innovactive Barrierferm preparation

INNOVACTIVE FERMENTATION STRATEGY

Bacillus Subtilis originally obtained from Natto (the oldest Japanese food) during soybeans lactic fermentation, is fermented in the laboratory under controlled technological conditions in a specific medium with natural substrates and natural origin peptides having cosmetic properties.

During fermentation process, Bacillus Subtilis sp. Natto produces several bio actives peptides and enzymes playing key roles in skin cells.

The INNOVACTIVE FERMENTATION STRATEGY to obtain a Ferment-Peptide Complex is based on the addition of peptide during natural fermentation of Bacillus Subtilis grown with plant-derived nutrients.

INNOVACTIVE BARRIERFERM

Ferment-Peptide Complex derived from natural fermentation in which Bacillus Subtilis grows in a specific medium including Acetyl heptapeptide-4 to synergize with peptides produced by
the bacteria.

KEY ACTIVE INGREDIENTS AND THEIR FUNCTIONS

At the end of fermentation, the bacteria are filtered and lysed to obtain a concentrate rich in active ingredient such as:

Peptides and enzymes are titrated as total proteins and specific enzymatic activities which together with the B Group Vitamins make the Ferment-Peptide Complex particularly effective in several activities.

In the BARRIERFERM particularly:

Bacillus Subtilis Ferment is a key for microbiota balance, barrier reinforcement, moisturizing and protective activity.

Acetyl heptapeptide-4 boosts the skin’s own defense system by promoting microbiota balance, diversity and growth of beneficial bacteria by improving skin.

INNOVACTIVE BARRIERFERM EFFICACY

IN VIVO EFFICACY TEST CARRIED OUT USING A CREAM
CONTAINING 3% OF BARRIERFERM

Evaluation of the moisturizing efficacy
after 15 minutes and 2 h

Evaluation of the protective activity
after 15 y 30 minutes

IN VIVO EFFICACY TEST CARRIED OUT USING A CREAM
CONTAINING 1% OF BARRIERFERM

Evaluation of the moisturizing efficacy
after 15 minutes and 2 h

Evaluation of the protective activity
after 15 y 30 minutes

TECHNICAL PRODUCT DATA

OTHER FERMENT-PEPTIDES

Green encapsulation of a functional combination of two active Ingredients to increase deep skin hydration for at least 72 hours.
An antioxidant/protective Ferment with Catalase and Lipase activity.
A lipo-reducing and remodeling ferment with body and face shaping activity.
A natural anti-microbial Ferment-Peptide Complex with a strong activity against bacteria pathogens and also C. Acnes.