Transformation of simple raw materials in a Ferment-Peptide Complex by a process that combines Natural ferment with a natural origin peptide
INNOVACTIVE BACILFERM
an antioxidant/protective Ferment with Catalase and Lipase activity

TECHNOLOGY
BIO FERMENTATION
EFFICACY STUDIES
Protective activity (TEWL)
Moisturizing activity
MIC evaluation including
C. Acnes
Protective action against
damages induced by H2O2
Antioxidant in vivo study
DOSAGE
3%
REGULATORY
EU AU CN KR US CA JP
Flowchart for Innovactive Barrierferm preparation
INNOVACTIVE BIO FERMENTATION
Production of unique bio ferments that contain well-selected peptides and peptides produced during the fermentation process.
Bacillus Subtilis originally obtained from Natto (the oldest Japanese food) during soybeans lactic fermentation, is fermented in the laboratory under controlled technological conditions in a specific medium with natural substrates and natural peptides having cosmetic properties.
During fermentation process, Bacillus Subtilis sp. Natto produces several bio actives peptides and enzymes playing key roles in skin cells.
Bacillus Subtilis: a universal cellular machine for industry agriculture, biomaterials, cosmetics and medicines.
INNOVACTIVE BACILFERM
a high quality and unique ferment with antioxidant properties titrated in key enzymes, biologically active peptides and B Group Vitamins.
KEY ACTIVE INGREDIENTS AND THEIR FUNCTIONS
At the end of fermentation, the bacteria are filtered and lysed to obtain a concentrate rich in active ingredient such as:
- Vitamins Group B/K2/C
- Biologically active peptides
- Antioxidants
- Peptides and Proteins
- Catalase enzyme
- Lipase enzyme
Peptides and enzymes are titrated as total proteins and specific enzymatic activities which together with the B Group Vitamins make the ferment particularly effective in several activities such as: antimicrobial, lipolytic, protective, antioxidant…
In the BACILFERM particularly:
Lipase Enzyme: acting on adipocytes will play an important role in tissue remodeling in the treatment of cellulite and in the face and body shaping contours.
Catalase Enzyme: essential to degrade H2O2 preventing skin oxidative stress and hair follicles oxidative damage that would contribute to appearance of gray hair as the reduction of melanin synthesis.
Group B Vitamins (especially B6): reinforce skin barrier, supply hydration, protects from pollution damaging factors while reduces acne, balance sebum and calms irritated skin by controlling UV skin sensitivity.
Biologically active peptides: with antimicrobial
activity help to balance skin microbiota, and
contribute as a preservative booster.
ANTIOXIDANT IN VIVO STUDIES
Carotenoids level measure

INNOVACTIVE BACILFERM EFFICACY
- Microbiota skin balance
- Barrier reinforcement
- Moisturizing effect
- Regenerating effect
- Protection against oxidative environmental induced damages (pollution, UV, blue light)
- Lipolitic activity
- Antimicrobial activity
- Catalase activity which stimulates the synthesis of melanin and delays the hair graying process related to the increase of Hydrogen Peroxyde (H2O2) in the hair follicles due a decreased catalase activity
PROTECTIVE ACTION AGAINST DAMAGES INDUCED BY H2O2

MIC EVALUATION (INCLUDING C. ACNES)

Technical product data
- INCI: Glycerin, Bacillus Ferment Filtrate.
- Solubility: water soluble.
- pH: 6-8.
- Colour: colorless-yellowish
- Preservative Free
- Recommended dose: 3%
Brochure
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